What Are Polynucleotides?

Advanced skin regeneration for smoother, healthier, more radiant skin

Polynucleotides are one of the most exciting advances in regenerative aesthetics. Unlike traditional injectables that focus on filling or relaxing lines, polynucleotides work at a deeper biological level to repair, rebuild and rejuvenate the skin. They are designed to improve skin quality from the inside out, restoring hydration, elasticity and structure for a naturally refreshed appearance.

What Are Polynucleotides?

Polynucleotides (PNs) are highly purified DNA fragments derived from natural sources. When injected into the skin, they stimulate healing processes, encourage collagen production and improve overall tissue quality. They are not fillers and they do not change the shape of your face. Instead, they help your skin function as it did years earlier.

How Do They Work?

Polynucleotides trigger a regenerative response within the skin. They activate fibroblasts (the cells responsible for collagen and elastin), increase hydration levels by attracting and binding water and calm inflammation. This makes them particularly effective for crepey skin, fine lines, dullness and areas that have lost elasticity. Most clients notice firmer, brighter and more supple skin after a course of treatments.

Key Benefits

• Improves skin elasticity and firmness
• Enhances hydration for a dewy, healthy glow
• Smooths fine lines and crepey skin
• Encourages collagen and elastin production
• Reduces inflammation and promotes healing
• Suitable for even delicate areas like under the eyes

Where Can Polynucleotides Be Used?

Polynucleotides are incredibly versatile and can be used on:
• Under-eyes (for dark circles and crepey texture)
• Face
• Neck
• Chest
• Hands
• Anywhere skin needs regeneration and support

What to Expect

Treatments involve a series of small injections placed in targeted areas. The procedure is quick, and downtime is minimal, though you may experience slight swelling or small bumps that settle quickly. For best results, a course of two sessions spaced a few weeks apart is recommended, with maintenance every six to nine months.

How Long Do Results Last?

Results develop gradually as your skin regenerates from within. You can expect improvements to last several months, with longevity increasing after completing a full treatment course.

Who Is This Treatment For?

Polynucleotides are ideal for clients looking for natural, regenerative results without adding volume. They’re especially effective for ageing, dehydrated or fragile skin and for clients wanting to improve texture without changing their facial structure.

If you’d like to learn more about how polynucleotides can rejuvenate your skin, a consultation can help you explore the best treatment plan for your goals.